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Early aortic stiffness in Psoriatic Disease: a three-phenotype comparison (PsO-only, PsO+PsA, PsA-only)

Authors

UNIDAD ENFERMEDAD PSORIASICA (UEP). Hospital San Juan de Dios, La Plata. Buenos Aires. Argentina
Maria Eugenia  Amoreo
H.I.E.A. y C. San Juan de Dios
Camilo Martinez
H.I.E.A. y C. San Juan de Dios
Jonatan Mareco
H.I.E.A. y C. San Juan de Dios
Mara Ivanov
H.I.E.A. y C. San Juan de Dios
Mariana Bernardo
CDYC. Clinica Dermatologica y Capilar
Lucia  Cordoba
H.I.E.A. y C. San Juan de Dios
Virginia Dimotta
H.I.E.A. y C. San Juan de Dios
Lucia  Martinez Gamba
H.I.E.A. y C. San Juan de Dios
Javiela Spinelli
H.I.E.A. y C. San Juan de Dios
Bruce Knudsen
H.I.E.A. y C. San Juan de Dios
Ana Sirera
H.I.E.A. y C. San Juan de Dios
Trinidad Pennini
H.I.E.A. y C. San Juan de Dios
Maria Jose Otero
H.I.E.A. y C. San Juan de Dios
Walter Espeche
H.IGA San Martin La Plata
Ricardo Olano
H.IGA San Martin La Plata
Antonio  Zurzolo
MedNova
Joana Celeste Vilte
H.I.E.A. y C. San Juan de Dios
Carolina Leiva
H.IGA San Martin La Plata
Maria Eugenia Gonzalez
MedNova
Maria Eugenia Braviz Lopez
MedNova
Maria Jose Martinez Barreto
H.I.E.A. y C. San Juan de Dios
Bruno Papini
MedNova

Keywords

subclinical vascular damage/ vascular risk
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    Psoriatic disease is a chronic inflammatory condition that can affect the skin (psoriasis), the joints (psoriatic arthritis), or both. In recent years, researchers have learned that psoriatic disease may also increase the risk of cardiovascular problems.
    Our study explored whether people with different forms of psoriatic disease show early signs of changes in their blood vessels, even before cardiovascular disease becomes apparent. We compared three groups of patients: those with psoriasis only, those with both psoriasis and psoriatic arthritis, and those with psoriatic arthritis only.
    We found that patients with psoriatic arthritis tended to have stiffer arteries than patients with psoriasis alone. Arterial stiffness is considered an early marker of cardiovascular risk because it may reflect changes in blood vessel health before symptoms develop. We also observed higher blood pressure values and increased levels of some inflammatory markers in patients with arthritis.
    These findings suggest that people with psoriatic arthritis may experience early vascular changes that could contribute to future cardiovascular disease. Recognizing these changes early may help healthcare professionals identify patients at higher risk and encourage strategies aimed at preventing long-term cardiovascular complications.